Iron Oxide Sol
Iron Oxide Sol is an aqueous-based colloidal iron oxide that can be used to trace mucociliary transport in humans and animals. BioTechPlex’s iron oxide sol can be easily tagged with technetium 99m for use as an insoluble radiotracer (Wales 1980). Technetium, with a half-life of 6 hours and an emission of 140 keV gamma rays, is an ideal isotope for such radiotracer studies.
BioTechPlex’s iron oxide sol is a superior product for use in radiotracer studies. Its use prevents the potential for metabiosulphite irritants to contaminate sulfur colloid preparations.
Instructions for labeling this colloid with technetium 99m will be provided with the purchase of the iron oxide sol.
References
Wales, K.A.*, Petrow H.G. and Yeates, D.B. Production of Tc-99m Labelled Iron Oxide Aerosols for Human Lung Deposition and Clearance Studies. Int'l. J. Appl. Radiation and Isotopes, 31:689-694, 1980.
Gerrity, T.R., Cotromanes, E., Garrard, C.S., Yeates, D.B. and Lourenco, R.V. The Effect of Aspirin on Lung Mucociliary Clearance. New Eng. J. Med., 308:139-141, 1983.
Yeates, D.B., Spektor, D.M. and Pitt, B.R. Effect of Orally Administered Orciprenaline on Tracheobronchial Mucociliary Clearance. European J. Respir. Disease, 69:100-108, 1986.
Piel, M.J., Griffin, C.L. and Yeates, D.B. A Technique for Measuring Bronchial Mucociliary Clearance in Unsedated Dogs. J. Aerosol Science, 17(6):985-997, 1986.
Yeates, D., Daza, A.V., and Mussatto, D.J. Bronchial and Alveolar Allergen-Induced Anaphylaxis and the Stimulation of Bronchial Mucociliary Clearance in Ragweed-Sensitized Dogs. Proceedings of the Association of American Physicians. 109:(4) 1-13, 1997.
Winters, S.L.* and Yeates, D.B. The Interaction Between Ion Transporters and the Mucociliary Transport System in the Dog and Baboon. J. Appl. Physiol. 83(4): 1348-1359, 1997.
Winters, S.L.* and Yeates, D.B. Role of Hydration, Sodium and Chloride in the Regulation of the Canine Mucociliary Transport System. J. Appl. Physiol. 83(4): 1360-1369, 1997.
Wang, L Tiniakov, R.L., and Yeates, D.B. Peripheral Opioidergic Regulation of the Tracheobronchial Mucociliary Transport System. J. Applied Physiol. 94(6):2375-83, 2003.
For more information on Iron Oxide Sol or to place an order, e-mail sales@biotechplex.com or call (760) 744-1000
